They can also make you feel weak, numb, dizzy, or confused. The number of burst tears is random between 6-11 and they have equal chance. Challenges Epic Fetus . Breakfast = +0.2 shot speed, +1.5 Range. Character Appearance Blood clots can form in veins anywhere in the body, including in the small veins under your skin or in the veins deep inside your body. Using it with less than 5 coins does nothing, UNLOCK: Unlock this item by collecting 99 coins then spending all of them in the same run, Item Pool: Item Room, Greed Mode Item Room, Upon use, grants use of Brimstone for the current room, If used twice in the same room, the brimstone laser becomes massive and deals +1.8 more damage, Using it more than twice in the same room will give a damage increase each time. Isaac takes a full heart if hurt by Blood Puppy and it drops a full red heart for every 10 enemies it kills. increased tears stat does not reduce the charge up time of Brimstone. Isaac's tears are replaced with a charged blood laser beam. If your speed stat is already higher then that value is still used, Upon use, Isaac charges in the direction the pony is facing, becoming invulnerable during the charge and damaging enemies while also casting the effect of Crack The Sky. Any Tarot card or rune on the floor or current held when picking this item up will change into a pill, Dice Shard counts as a card and will be converted, UNLOCK: Unlock this item by picking up 2 of the following items: Roid Rage, The Virus, Growth Hormones, Experimental Treatment or Speed Ball, * shop room pool, shop item pool, brown, purple, * boss room pool, boss room item, red, wedge, purple, triangle, The above stats only apply to tears fired from Isaac's left eye or with a 50% chance if you have an item which causes you to fire from a single source only, * boss room pool, boss room item, red, blob, circle, spot, * boss room pool, boss room item, grey, gray, Enemies touching placed bombs take 16 damage, Gives all bombs a burning effect when they explode, leaving fire on the floor which deals 22 damage to enemies, REPENTANCE - Hot Bombs now have greatly increased contact damage (increased from 1 to 16), and passively grants Isaac immunity to fire, * item room, treasure room, item room pool, fire, orange, flame, face, Isaac's tears now set enemies on fire, leaving a damage over time effect that does 4 or 6 damage per tick, There is a chance that tears that hit enemies will explode, leaving a small fire on the floor that damages enemies, Exploding tears deal damage * 2 + 22 per tick, The chance for tears to explode is affected by your luck stat and at +13 Luck it will activate every time, * item room, treasure room, item room pool, fire, flame, orange, back, ball, burning, When picked up, and at the start of each floor this rerolls all your current items, giving you a new item to replace each of the ones you had, Also rerolls all your stats at the same time, giving a random flat modifier that changes each time, Doesn't affect important items such as Polaroid, Negative and Key Pieces, UNLOCK: Unlock this item by beating Boss Rush with Lazarus, * secret room pool, mondrian, painting, yellow, blue, red, white, Tears now have a chance to apply the fear effect to enemies, which causes them to run away from Isaac, The chance to fear enemies is affected by your luck stat and at +20 Luck it will activate every time, An item only found in the devil room pool (Note: The Fallen boss pulls items from the Devil Room Pool), * devil pool, devil room pool, devil deal, grey, gray, fist, glow, Immunity to all floor curses (e.g. Lil Clot spawns in a random location near Isaac when the trinket is first picked up. ?s soul, blue baby's soul, blue babys soul, When you kill an enemy, you have a chance to get +0.5 damage up for the current room, UNLOCK: Unlock this item by beating the Dark Room with Samson, *, hair, pony, tail, brown, red, samsons lock, Gives a 25% chance to reveal map icons at the start of a new floor (The same effect as the Compass), UNLOCK: Unlock this item by beating the Chest with Cain, When you kill an enemy, you have a chance to spawn a transparent Dead Bird familiar, The Dead Bird familiar deals 2 damage per tick to enemies while in contact with them, UNLOCK: Unlock this item by beating the Isaac boss with Eve, *, grey, gray, black, striped, eves bird foot, REPENTANCE - No longer replaces chests that have already spawned, UNLOCK: Unlock this item by beating Ultra Pride, * northernlion, drop the left hand, paw, bloody, bleeding, grey, gray, While held, tinted rocks and rocks with a crawlspace below them will flash white every 10 seconds, *, grey, gray, silver, lump, metal, stone, Turns all troll bombs into bombs which you can pick up and use, Super Troll bombs turn into 1+1 free double bomb pickups, Gives your tears a random worm effect every few seconds, The possible tear effects include: Whip Worm, Ring Worm, Wiggle Worm, Flat Worm, Hook Worm, Pulse Worm, Tape Worm and Lazy Worm, While held, Tape Worm doubles your range stat and halves your tear height stat, Every time you get hit, you have a chance to activate the D6, D20, D8, D10 or D12 effect. Unlock Method One of the sounds lasers can make when synergizing with Monstro's Lung. You can pick which dice you want to use. Ultra Secret RoomTreasure RoomTreasure Room Every 6 coins Bumbo will evolve to a new form except for level 4 which takes 12 coins, Level 2: Bumbo gains a body and crawls around the room, sometimes dropping random pickups, Level 3: It now fires tears in the same direction Isaac does, Level 4: Bumbo no longer fires tears but instead will chase enemies slowly and deal contact damage. UNLOCK: Unlock this trinket by collecting three of the following in the same run: Magic 8 Ball, Tiny Planet, Crystal Ball, Star of Bethlehem or any of the Astrology-related items (e.g. Endings. Does BFF affect rotten baby? Endings. Amount changed equals the equivalent stat up/down pill. It returns after a room has been cleared, UNLOCK: Unlock this item by beating Greed Mode with Eden, Item Pool: Item Room, Secret Room, Greed Mode Shop, *, red, yellow, green, white, square, rectangle, When used, the D8 rerolls all of your stats, Will only effect your damage, tears, range and speed stats, Each stat is given a multiplier that applies after all other adjustments, UNLOCK: Unlock this item by beating Challenge #28 (Pride Day), * dice, pip, die, black, grey, gray, pyramid, triangle, Purity will boost one of Isaac's stats depending on the colour of the aura around him, When you take damage, the aura will be removed and replaced with another random one when you enter the next room, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Maggy, Item Pool: Item Room, Angel Room, Greed Mode Item Room, Greed Mode Angel Room, Adds a chance for a black ring to spawn around killed enemies, dealing damage to others that touch it, The ring damage scales with your tear damage, The change for a ring to spawn scales with your lucky stat, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Eve, Item Pool: Devil Room, Curse Room, Greed Mode Devil Room, *, grey, gray, silver, metal grabber, hand, robot, When Isaac has no red hearts, this item gives Isaac the ability to fly. 25 Of The Best Items In The Binding Of Isaac. ), which return as little balls of blood and deal 3x . or the path they take (My Reflection, Tiny Planet etc. Counts as 1 of 3 evil items needed towards the Leviathan transformation. Rooms ( : Bum Friend The Peeper Ghost Baby Harlequin Baby Daddy Longlegs Sacrificial Dagger Rainbow Baby Holy Water Guppy's Hair Ball Abel), Others: 1UP The Virus Less Than Three Skeleton Key A Dollar A Quarter Boom! Doesn't include Curse Room doors or spiked rocks, Tears can be controlled mid-flight using the directional keys, In addition to regular tears, Isaac will sometimes fire extra spectral tears that orbit around him, Fully heals all your red heart containers, Isaac now emits a large light aura that damages nearby enemies 5 times per second while touching it, The visual effect is similar to the effect given to tears by the GodHead item, The aura deals more damage towards the center, ranging from 0.75 at max range to 4 damage when touching Isaac, In addition to normal tears, Isaac now also fires a set of 4 quadshot tears with a slowing effect, The quadshot tears deal 1.5 damage each and do not scale with your damage upgrades, Upon taking damage, you have a chance to dislodge the spider from your face. Killing a petrified enemy will freeze it. Frogsplat Apr 2, 2014 @ 5:11pm. Each brimstone laser deals 8 damage per tick for 13 total hits. Blood Clot DMG + range up . It rerolls enemies and pickups it comes into contact with, then despawns. Charge amount increases the barrage size; 2-4 knives at 0%, 8-10 knives 100%. Trinkets If you get hit in either of the other 2 states you will not be teleported, The Black Candle item will remove the Cursed Eye's teleportation effect, REPENTANCE - Burst now has 5 shots instead of 4, * secret room pool, item room, treasure room, item room pool, white, circle, pearl, When Isaac's tears hit anything, they leave a green toxic creep on the floor that damages enemies for 1 damage per tick, * item room, treasure room, item room pool, mystery liquid, grey, gray, green, A familar that is attached to Isaac, which will seek out and damage any enemies close by for 3 contact damage, * astrology, astronomy, item room, treasure room, item room pool, blue, glow, A familiar eye that follows Isaac and copies all his tear modifiers/effects, but shoots in random directions, Tears from this familiar deal 75% of Isaac's tear damage, UNLOCK: Unlock this item by beating Boss Rush with Cain, * item room, treasure room, item room pool, eyeball, white, circle, cataract, cains other eye, A familiar fly that can be moved around via use of the arrow keys dealing 2.5 contact damage per tick, similar to the Ludovico Technique's mechanic, UNLOCK: Unlock this item by beating Boss Rush with Blue Baby, * item room, treasure room, item room pool, blue fly, big fly, blue baby's only friend, fat, dead, ?? DQY7 QK7M (The Basement XL: Second boss's Devil Room), PC QFJL Q6SC (One of the chests in Curse Room adjacent to spawn), PC QW44 N10D (Second floor Devil Room; Isaac may proceed normally, but all other characters must not enter the first floor Treasure Room. Increases the maximum heart limit to 18. You may see more or less than this on the Found HUD overlay, however this number varies based on your other damage increasing items. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, from Fireplaces, Gives you a familiar which is a smaller version of the Plum boss, which sprays tears and propels itself around the room, Deals 2 contact damage per tick to enemies, and the tears deal 3 damage each, Deals contact damage to any enemies it runs into, UNLOCK: Unlock this item by beating Baby Plum 10 times, When used, this item calls a friendly version of the Plum boss to fight for you for 10 seconds, It will jump to the nearest enemy, slam on the ground and fire tears around it, then propel itself around the room, dealing contact damage to any enemies it touches before disappearing, It's possible to get a guaranteed spawn of this item by encountering the Baby Plum boss and not damaging her. Unlocked from Challenge #24 - PAY TO PLAY, Power Pill - Gives you invulnerability and the ability to damage enemies for a short while (similar to The Gamekid effect), Re-Lax - Causes Isaac to spawn poops behind him while he walks for a few seconds. This does not work with items that grant a charged attack but also override Technology's costume, e.g. Literature. Midnight Snack = +1 flat damage, +1 luck. Blood Clot doesn't work with Lilith since she . Devil Rooms / I AM ERROR rooms, UNLOCK: Unlock this item by defeating Mother as Apollyon, You gain a familiar that lives under the floor. Stat Down becomes Stat Up, 'Bad Trip' turns into 'Balls of Steel' and 'Amnesia' turns into 'I can see forever', * astrology, astronomy, item room, treasure room, item room pool, blue glow, m, Balances out your main stats to bring the high and low stats closer to an average value, All future stat upgrading items will now instead spread out across all other stats. Does not apply to locked chests, * item room, treasure room, item room pool, red, horse shoe, Reveals the entire map for every floor except the secret room locations, Does not show the icons for any unexplored rooms, Can still help you to guess which direction the boss room is in, due to the fact that the Boss Room is usually in the room furthest away from the first room, * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, Completion Marks Modes ?, Satan and The Lamb as Tainted Judas, Changes Devil Room layouts. Pressing 3 yellow buttons on the floor causes the minecart to be rideable. Frozen enemies can be pushed into obstacles where they shatter on contact and fire ice shards around them. Mom's Knife gives Incubus a smaller version of the item with the same base range as Isaac; However, . Challenges . starting, blue, white, glow, cross, You can now break obstacles by walking over them, Holes in the ground can be filled by crushing adjacent rocks, similar to how this can be done with bombs, * item room, treasure room, item room pool, cheetos, cheese, grey, gray, orange, jar, Enemies and pickups (keys, bombs etc.) Rarer clots have unique effects on tearsBone Clot tears have Compound Fracture, Gold Clots have Midas Touch, Eternal Hearts have Sacred Heart, and Black Hearts have Dark Matter. Rooms in The Chest as Apollyon, Upon entering a room with enemies, spawns a Black Locust that deals quadruple Isaac's damage, applied as two hits of double damage, UNLOCK: Unlock this trinket by defeating The Lamb as Apollyon, At the start of each new hostile room you spawn 2-5 white attack flies, which will target a nearby enemy and deal double your tear damage to it, UNLOCK: Unlock this trinket by defeating Boss Rush as Apollyon, When killing an enemy, you have a very small chance to gain the ability to fly for the rest of the room, UNLOCK: Unlock this trinket by defeating Greedier Mode with Azazel, Stem Cell heals Isaac's red heart containers to 50% each floor, If Isaac already has 50% health or more, it heals half of a heart instead, UNLOCK: Unlock this trinket by defeating Greedier Mode with Samson, Fully recharges your active item at the start of each boss fight, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Zaratus, Gives you the Holy Mantle shield effect at the start of every new floor, which protects you from the next hit of damage you take, Does not recharge until the start of the next floor, Stacks with the effects from Holy Mantle and Blanket, but it does not stack with Holy Card, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Ep and Mills, Using your active item while holding this trinket will drop it back on a pedestal on the ground, Also after taking damage, you have a very small chance to drop one of your passive items, One-time use active items will be consumed and not dropped, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by MarkusLeben and iguesti, *, yellow, golden, box, block, square, cube, Holding this trinket will cause the Angel mini bosses to drop normal items instead of Key Pieces, Added as part of the Afterbirth+ Booster Pack #2, designed by Edmund McMillen, While held, the last door Isaac went through stays open, allowing him to leave the room even if enemies are in it, This trinket works on boss rooms (except Ultra Greed) and devil rooms containing Krampus, allowing you to exit out mid-fight, UNLOCK: Unlock this trinket by blowing up doors and secret room walls 50 times, *, door, stop, wedge, cheese, wood, brown, hodor, game of thrones, Wylis, After being picked up, a yellow laser chain now flows through Isaac's familiars, Added as part of the Afterbirth+ Booster Pack #4 and based on the Steam Workshop mod created by Strawrat and Aczom, While held, spawns +1 friendly blue fly every time you pick up a coin, Added as part of the Afterbirth+ Booster Pack #5. EDIT: NL now has Dead God, items are no longer bolded. Each room is locked to a specific trinket effect, meaning if you exit and re-enter a room, that specific room will always have the same effect. If you have PhD it will only increase one stat, Can be used multiple times, but every time you use it, it has a chance to disappear, The Gold Pill can spawn as a Horse Pill, which then causes it to give random Horse pill effects, UNLOCK: Unlock this by defeating Mega Satan as Tainted Cain, Horse Pills rarely spawn as larger versions of normal pills with more powerful effects, Items that synergize with pills also have the same effect with Horse pills, In general, the effect of a Horse Pill is double the effect of a normal pill i.e. Seeds ItemID: 254 "DMG + range up" +1.0 Damage Up (Left eye only). For the current room, tears now have the Spoon Bender effect, which allows them to curve towards enemies and gives them a purle appearance. Here's how to unlock each tainted character and what makes . With poison effects, the damage over time poison will last for much longer. Jun 05, 2008 |. When the effect wears off, Isaac quickly runs between each marked enemy, dealing high damage to each one rapidly (roughly x2.5 your tear damage), The damage caused by this effect scales up with every target it hits in a row, UNLOCK: Unlock this item by defeating Delirium as Tainted Judas, *, budas, jubas, sword, blood, omae wa mou shindeiru, When used, Abyss consumes all pedestal items in the current room and converts them into Red attack flies, Red attack flies will charge across the room in the same direction Isaac is shooting, dealing contact damage to enemies equal to Isaac's tear damage, The flies don't block enemy shots, but this also means they never die and stay with Isaac forever, UNLOCK: Unlock this item by defeating Delirium as Tainted Apollyon, Staples one of Isaac's eyes shut, meaning he only shoots tears from one eye. Quality - Speeds up all enemies for the rest of the room. Fires 3-5 additional beams in random directions around Isaac. rocks), Item Pool: Item Room, Devil Room, Greed Mode Devil Room, * item room, treasure room, item room pool, luigi board, weeja board, paper, grown, Automatically gives you 1 bar of charge after using your spacebar item, Fully recharges your current spacebar item when picked up, Any items which are normally a 1 room recharge are now timed instead, * shop room pool, shop item pool, battery, black, brown, When Isaac takes damage, the dead bird will spawn and attack nearby enemies in the current room for 2 damage per tick, * item room, treasure room, item room pool, the lost item pool, starting, grey, gray, Tears are replaced with the ability to charge and fire a powerful laser that travels in a straight line across the room, dealing a lot of damage (tear damage hits for 9 ticks per laser) to any enemies it comes into contact with, Does not directly affect your Damage stat but hits enemies 9 times per charge, Synergizes very well with a lot of items including Tammy's Head, Tiny Planet, Inner Eye (Triple Shot), Mutant Spider (Quad Shot) and many others, If you somehow manage to get a second Brimstone, the laser becomes massive and deals double damage, * devil pool, devil room pool, devil deal, infinity, red, black, Has a chance to drop while playing any Blood Donation machine, UNLOCK: Unlock this item by playing the Blood Donation machine 30 times, Item Pool: None (Blood Donation machine only), Gives you a high rate of fire in exchange for a damage down, * secret room pool, item room, treasure room, item room pool, Thin Odd Mushroom, brown, purple, grey, gray, REPENTANCE - Odd Mushroom (thick) is now a larger damage increase (equal to that of Steven/Pentagram), but now also a larger speed downgrade (from -0.1 to -0.2), * secret room pool, item room, treasure room, item room pool, purple, pink, brown, thick odd mushroom thick, When you only have half a red heart remaining or less, you enter a curse state which adds +1.5 damage and +0.3 speed, When playing as Eve, this item activates with one FULL heart remaining or less AND also removes her 0.75 damage multiplier, raising it up to 1.0, The effect is permanently active for characters with no red hearts (e.g. Secret Rooms, UNLOCK: Unlock this trinket by defeating Mother as Tainted Lazarus, Every time you take damage, you drop up to 2 different types of consumables on the ground, Dropped consumables can be any variant of its kind - e.g. Sad Bombs: Bob's Brain will fire tears upon exploding. Each time you clear a room there is a chance a Red Room will spawn at one of the walls. Explosion damage has increased to 100 (from 60). Collection Grid Heart - 26.6% chance, Trinket - 6.6% chance. 3c pickups become 2c, Taking more than 1 steam sale reduces the price of all items even further, This item is called Steamy Sale on PS4, PS Vita, Xbox One and Switch versions, probably due to copyright reasons, Item Pool: Shop, Greed Miniboss, Shopkeeper, * shop room pool, shop item pool, red, pink, white, paper, Spawns 6 troll bombs at random locations around the room, Bombs are effected by other passive bomb items, Has a chance to drop from the Pride miniboss fight, Item Pool: Item Room, Library, Pride Miniboss, * Anarchist's Cookbook, Anarchists Cookbook library pool, library room, book room pool, item room, treasure room, item room pool, They do not block enemy shots, UNLOCK: Unlock this item by defeating The Beast as Tainted Lilith, Isaac builds rage each time you clear a new room. shop room pool, shop item pool, cross, brown, Upon use, gives +2 damage up which lasts for the current room, x1.5 times Damage Multiplier if you also have Blood of the Martyr (Does not stack with Magic Mushroom or Cricket's Head multipliers), Increases your chances of getting a devil/angel room by +12.5%, REPENTANCE - The effect stacks if used multiple times, * library pool, library room, book room pool, devil pool, devil room pool, devil deal, starting Curses For example if the spawned boss leaves creep, it can damage Isaac, UNLOCK: Unlock this item by defeating Delirium for the first time on any character, A familiar fly that orbits around a random enemy in the room until that enemy dies, dealing 2 contact damage to other enemies, Angry Fly will move to the next enemy after the one it is currently orbiting dies, until the room is cleared, at which point it will return to orbiting Isaac, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Custom Phase, UNLOCK: Unlock this item by transforming into Beelzebub (Achieved by picking up 3 fly related items, see Transformations page for full list), A throwable active item that places a black hole on the ground where it lands, sucking all enemies into it for 6 seconds, Enemies stuck inside the black hole take rapid damage over time, The Black Hole will also suck Isaac into it, but with a much weaker effect than to enemies, The Black Hole will destroy nearby obstacles such as rocks and pots, Adds a random chance for an enemy in the current room to become charmed or feared briefly, Adds a random chance to spawn a rainbow poop upon taking damage, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Electoon, UNLOCK: Unlock this item by breaking 5 rainbow poops, *, red, white, stripe, hat, clown, waldo, wally, Causes random enemies to 'lag' at random intervals, causing them to freeze in place for a second, The lag effect can also apply to tears, projectiles and consumables on the ground, While held, this item has a 25% chance to double up any end of room drops (similar to the Contract from Below effect), Isaac's Luck stat affects how often the lag effect occurs, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Freezenification, UNLOCK: Complete 7 Daily Challenges (30 on console), A one-time use item that spawns a random item from the current room's item pool, with a chance for it to spawn Lump of Coal or The Poop instead, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Mills, *, green, red, present, bow, xmas, christmas, When used, spawns a Sprinkler that rotates in a circle, spraying tears in all directions, Will also synergize with some other items, such as Mom's Eye, Brimstone, Dr. Fetus, Tech X or Loki's Horns, Added as part of the Afterbirth+ Booster Pack #1 and based on the Steam Workshop mod created by Kieran and Stewartisme, Allows you to rapidly place bombs on the ground, Added as part of the Afterbirth+ Booster Pack #1. 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